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In addition to you watching for changes in your own symptoms, your family or other caregivers should be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment. <li>Do not use sertraline if you are using pimozide (Orap), or an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam). Serious and sometimes fatal reactions can occur when these medicines are taken with sertraline. 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Do not take extra medicine to make up the missed dose. </ul> <b>What happens if I overdose? </b><ul> <li>Seek emergency medical attention if you think you have taken too much of this medication. Symptoms of a sertraline overdose may include dizziness, drowsiness, nausea, vomiting, rapid heartbeat, agitation, tremor, confusion, seizures, and coma. </ul> <b>What should I avoid while taking sertraline? </b><ul> <li>Do not take sertraline together with pimozide (Orap), isocarboxazid (Marplan), phenelzine (Nardil), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate). <li>Avoid drinking alcohol, which can increase some of the side effects of sertraline. <li>Avoid using other medicines that make you sleepy (such as cold medicine, other pain medication, muscle relaxants). They can add to sleepiness caused by sertraline. <li>Sertraline can cause side effects that may impair your thinking or reactions. 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Talk to your doctor about any side effect that seems unusual or that is especially bothersome. </ul> <b>What drug(s) may interact with sertraline?</b> <p>Sertraline has the potential to interact with a variety of medications, check with your healthcare professional. 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